Position Responsibilities:
The successful candidate will apply state-of-the-art expertise in cellular and molecular biology, proteomics, biochemistry, and computational analysis to advance drug-discovery research.
Position Summary
Design and interpret mass spectrometry-based proteomic experiments across multiple research projects and platforms. Design and execute complex cellular, biochemical and mass spectroscopy experiments to elucidate biomarkers and mechanism-of-action in phenotypic screens. The ability to analyze complex datasets as well as interpreting the results into a biological context is critical for this position. Work with teams of scientists across global Vertex locations to execute experiments, coordinate all aspects of sample data handling, data analysis, and biological interpretation. Presentation and participation in interdisciplinary project teams is expected.
Position Responsibilities
• Ability to work across multiple projects simultaneously.
• Conduct complex cellular experiments with sophisticated design and execution.
• Extensive proteomics sample handling and preparation experience.
• Thorough data analysis and critical reviews of ongoing activities.
• Effective project planning, documentation, and presentation skills.
Position Qualifications:
A Ph.D. in biochemistry, biology, or a related area with at least 4+ years’ experience.
• A proven track record in cell culture methods and protein handling expertise for challenging biochemical and proteomics studies.
• Working knowledge of MS based computational software such as MASCOT, Protein Discoverer, Pinpoint, Excalibur, Analyst, as well as multivariate data modeling software.
• Familiarity with isotopic labeling, bioinformatics, statistics, and transcript profiling is desirable.
• Excellent communication and presentation skills.
Vertex creates new possibilities in medicine. Our team discovers, develops and commercializes innovative therapies so people with serious diseases can lead better lives. Vertex scientists and our collaborators are working on new medicines to cure or significantly advance the treatment of hepatitis C, cystic fibrosis, rheumatoid arthritis and other life-threatening diseases. Founded more than 20 years ago in Cambridge, MA, we now have ongoing worldwide research programs and sites in the United States, United Kingdom and Canada. Vertex has consistently been recognized as one of the industry's top workplaces by leading publications such as Science Magazine, The Boston Globe, Boston Business Journal, San Diego Business Journal and The Scientist, For more information and to view Vertex's press releases, please visit www.vrtx.com.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
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