The Department of Pediatrics, division of Systems Medicine is seeking a Bioinformatics Specialist. He/She will conduct research and development in biomedical informatics and biostatistics, by architecting, developing, maintaining, and documenting a bioinformatics software infrastructure that integrates disparate forms of clinical and genomic data and offers other evolving capabilities to support research activities. Responsibilities for this position include, (1) to develop and implement novel computational techniques in software that can reanalyze public repositories of clinical and genomic data, (2) to design, implement, and support novel software tools that allow for complex, biologically-driven queries across multiple types of data, (3) to manage third-party programming services in the development, documentation, and release of public bioinformatics resources, (4) to propose, research, and develop novel bioinformatics methods and techniques to support new research, and (5) to consult with collaborating faculty and staff with regards to bioinformatics aspects of shared research endeavors. This employee will also be responsible for publishing novel bioinformatics findings and developments in appropriate professional journals and may be required to present aspects of bioinformatics work at conferences and workshops.
This position requires expert proficiency and strong experience in a number of technical and bioinformatics aspects. Strong experience and proficiency with (1) compiled (e.g. C, C++, Java) and interpreted (e.g. PERL, Python, Ruby) programming languages, (2) statistical or engineering software (e.g. Matlab, preferably R), (3) relational database management systems such as MySQL or Oracle, (4) structured data file format approaches such as XML or RDF, (5) web-server and web-services technologies and tools, such as PHP, JSP, or SOAP (6) the use of common bioinformatics tools and algorithms, such as BLAST, SAMR, NCBI and EBI eUtils, and (7) knowledge mining technologies such as Weka and semantic web technologies, and (8) the use of high-performance computing (HPC) management software such as Sun Grid Engine (SGE), PVM, or MPI or cloud-based computing (e.g. Amazon, or others), is required. Additionally, the employee is required to have experience in a number of bioinformatics domains including, (1) genomic sequence analysis, (2) gene expression analysis, (3) comparative genomics and phylogenetics, (4) proteomics, and (5) analysis of genetic variation within species and across populations. Strong experience in data mining and statistics is a must. The candidate must have a high level of integrity and excellent judgment concerning privacy issues. Prior experience in writing and publishing scientific manuscripts is a must. Prior background in immunology or infectious disease or clinical trials is a strong plus. Strong written and oral communication skills in English are essential.
Four year degree in Computer Science, Bioinformatics, Computational Biology, Biomedical Computation, Biomedical Informatics or related field required. Advanced degree preferred. 7 years of applicable experience required, 10 or more years are preferred.
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