Department Description | | | | | | | | Research in the laboratory of molecular biology aims to identify the genes, circuits, cells, macromolecular assemblies and individual molecules that contribute to the function and dysfunction of the mammalian brain. Scientists in the laboratory of molecular biology have developed a suite of novel approaches based on the manipulation of bacterial artificial chromosomes (BACs) to investigate the histological and functional complexities of the mammalian brain in vivo and to understand how these mechanisms become dysfunctional in disease. | | | | Detailed Description | | | | | | | | Will be responsible for detailed bioinformatics and biostatistical analysis of large scale next generation sequencing (NGS) data sets. Will be responsible for genomic alignments of all sequencing data as well as quality control, differential expression, comparative analysis, and other informatics. Will advise and work with investigators on proper experimental design and strategies for data analysis. | | | | Job Requirements | | | | | | | | Master's degree in science required; educational emphasis in biostatistics or bioinformatics preferred. Must be a professional informatics specialist with advanced training and be knowledgeable of various statistical packages and software, and programs used for NGS analysis, such as: Galaxy, Tuxedo suite, R, Star, Avadis NGS, GeneSpring GX and Ingenuity Pathways. A good working knowledge of Linux, Perl, and Python is also preferred. | | | | Additional Details | | | | | | | | | | | | | | | | | |
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