Overview
This course will provide an overview of key issues that affect metabolomics studies,bioinformatics tools, and procedures for the analysis of metabolomics data. It will be delivered using a mixture of lectures, computer-based practical sessions and interactive discussions. The course will provide a platform for discussion of the key questions and challenges in the field of metabolomics.
Audience
This course is aimed at PhD students and researchers with a minimum of one year’ s experience in the field of metabolomics who are seeking to improve their skills in metabolomics data analysis. Participants must have experience using R (including a basic understanding of the syntax and ability to manipulate objects) and the UNIX/LINUX operating system.
Syllabus, Tools and Resources
During this course you will learn about…
- Metabolomics study design, workflow and sources of experimental error
- Metabolomics data processing: R, XCMS, MetFrag, NMR tools, …
- Metabolomics data analysis: R, Bioconductor, data fusion, univariate and multivariate data analysis, data clustering and correlation methods…
- Metabolomics downstream analyses: MetExplore, Cytoscape plugin, metabolic pathway analysis, visualisation, differential expression, metabolomics flux.
- Metabolomics standards and databases: data dissemination and deposition in EBI-MetaboLights, ISATools and COSMOS
Learning Objectives
After this course you should be able to…
- Discuss major principles of metabolomics experimental design and factors that impact upon subsequent analysis
- Identify strengths and weaknesses in a variety of metabolomics analytical approaches
- Use a range of Bioinformatics software to pre-process, process and analyse metabolomics data
- Discuss current trends and challenges in metabolomics
Application registration closes 17 January 2014 (12:00 midday GMT). There will be a maximum of 25 participants on this course. Successful applicants will be notified by 31 January 2014 and will then be asked to confirm their place on the course by re-registering and paying the course fee.
Contact: Reza Salek , EMBL-EBI & Cambridge University, UK
Contact:
Reza Salek , EMBL-EBI & Cambridge University, UK
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