Bioinformaticist for Genomics Facility (Fixed Term 3 Years) Institute of Biological, Environmental & Rural Sciences Grade 6: £25,504 - £30,424

Bioinformaticist for Genomics Facility(Fixed Term 3 Years)

_{Institute of Biological, Environmental & Rural Sciences}

_{Grade 6: £25,504 - £30,424}

A position is available to provide a high-throughput genomics laboratory with bioinformatics support, primarily data manipulation and analysis. The post-holder will assist a laboratory team by developing scripts for processing large genotyping datasets (automated pattern finding, data sorting/transformation and conversion of datasets into suitable formats for downstream analysis software packages). They will also help develop pipelines for manipulation and analysis of next-generation sequencing data for gene expression and genotyping-by-sequencing studies. The post-holder will also liaise with other computing staff at AU to develop bioinformatics links between the laboratory and the IBERS bioinformatics infrastructure. The post may suit computer scientists wishing to work in bioinformatics but applicants with experience of dealing with high throughput sequencing projects and/or knowledge of genetic data would be preferred. Skill in at least one programming language (Perl, Java, C/C++) is required.

Ref: IBERS.13.05 1

Ref: IBERS.13.05

_{Closing date: 14 March 2013}

For information and application forms please go to http://www.aber.ac.uk/en/hr/jobs/vacancies-external/

Completed Applications Forms should be signed and returned to the HumanResources

_{RecruitmentTeambye-mail,fax orpost.Emailaddress:vacancies@aber.ac.uk /Tel:}

_{01970 628555 / Fax: 01970 622975}

NOTE: Please put the post reference on the front of your envelope and on your application form.

We are a Bilingual Institution which operates a Welsh Language scheme and is committed to

_{Equal Opportunities.}

APPOINTMENTS ARE NORMALLY MADE WITHIN 4-8 WEEKS OF THE CLOSING DATE. IF WE HAVE NOT BEEN IN TOUCH WITHIN THIS TIMESCALE YOU MAY ASSUME THAT YOUR APPLICATION IS NOT BEING FURTHER CONSIDERED AND NO OTHER COMMUNICATION WILL BE SENT.

FurtherParticulars(YnSaesneg yn unig) MainDuties& Responsibilities

The post holder will assist Dr Matt Hegarty and his group in bioinformatic analysis of next- generation sequence and high-throughput genotype data from a range of projects (plant, animal, bacterial), both in order to develop new computational tools for these types of experiment and/or integrate available software into a pipeline. The datasets involved are extremely large (tens of millions of DNA sequences, thousands of genotyping markers) and require manipulation to allow them to be analysed in different commercial software packages, as well as the development of some bespoke analysis tools. This will require development of scripts in programming languages such as R, Perl or Python. The post holder will also assist with integration of data produced by the Translational Genomics facility with the High- Performance Computing cluster, requiring familiarity with transfer of data between Windows and Linux operating systems and the ability to write scripts to automate data processing tasks which are currently performed manually. The post holder will be expected to be involved with the production of manuscripts for publication in international scientific journals and the supervision of postgraduate students on projects with a bioinformatics element. They will also be expected to coordinate with other members of the IBERS bioinformatics community to communicate new developments and ensure that data sources such as Translational Genomics and the National Plant Phenomics Centre are well-integrated. Presentation of bioinformatics data or tools at scientific symposia may also be required.

This job description is subject to review and amendment in the light of the changing needs of the University, to provide appropriate development opportunities and or the addition of any other reasonable duties.

Essential criteria

1. PhD or equivalent experience in bioinformatics, biological science or computer science.

Physical scientists with good computational skills, who are interested in converting to computational biology, are also welcome to apply.

_{2. Experience with analysing large data sets.}

3. Expertise in at least one programming language (Python, Perl, Java, C/C++).

_{4. Experience with the Linux operating system.}

5. Ability to communicate well as well as an ability to work well as part of a research team.

Ref: IBERS.13.05 2

6. Ability to interact effectively with others within IBERS and in the wider plant bioinformatics community

Desirable criteria

1. Experience in next-generation sequencing (NGS) data manipulation and analysis preferred. Some training can be provided in-house, but if needed the post-holder may be required to visit other genome centres (e.g. TGAC, Norwich) for extended periods.

2. Experience of gene expression analysis and/or SNP identification using NGS or other systems.

_{3. Knowledge of the use of markers for genetic analysis of plants and for plant breeding.}

7. Standard methods of eukaryotic sequence analysis, including use of large DNA

_databases.

8. Experience in use of genotype data for population genetics or marker/trait association analysis.